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Activity Funded

Egas Moniz Interdisciplinary Research Center

Centro de Investigação Interdisciplinar Egas Moniz

Reference
UIDB/04585/2020
Project Start Date
2020-01-01
Project End Date
2024-12-31
Principal Investigator
Scientific Area
Medical and health sciences
Funding Program
Concurso de avaliação no âmbito do Programa Plurianual de Financiamento de Unidades de I&D (2017/2018) - Financiamento Base

Abstract

10.2 Summary in English for general dissemination purposes CiiEM (Egas Moniz Interdisciplinary Research Centre) is the Centre for interdisciplinary and translational research and innovation of Egas Moniz. It is closely integrated with the community through Egas Moniz teaching, services and support activity. The Centre aims to develop the scope and quality of its activity through the following programme over the next 5 years: 1. Consolidating the ongoing organization of the Research Centre The existing functional structures of CiiEM will be monitored, tuned and provided with the resources for smooth functioning. CiiEM will create an editorial committee to take care of publications related to internal communication and with outside society. 2. Taking full advantage of the operation of its research areas to boost project applications and qualitative and quantitative scientific output The research areas provide a paradigm to address the main research topics within CiiEM and network the laboratories into complex projects. This will lead to more projects and publications, as well as improving the quality of the research, as it becomes more visible and accessible to discussion. The research areas also ensure that strengths are optimised, which will lead to an improved use of resources. 3. Enhancing external cooperation and participation in national and international scientific networks The CiiEM Board of Directors, Heads of the Research Areas and Laboratories and individual researchers are increasingly active in the wider scientific community to empower and enhance their research. Initiatives for international contacts and cooperation have met with successful results and will continue to be strongly encouraged and further developed. 4. Extending the involvement of CiiEM in post graduate teaching activities (PhD) With the onset of the Egas Moniz PhD programme, the CiiEM researchers and infrastructures will host more PhD students and participate in their orientation, extending and upgrading the work currently being carried out in the training of graduated and post-graduated students. 5. Organizing communication and dissemination activities An International Congress will be organized once a year, developing from and drawing on the experience of the two CiiEM congresses which have already been held. Extended abstracts will be published in a high-impact peer-reviewed international journal. Other regular public meetings of the CiiEM research areas and laboratories will be organised. Initiatives directed to the spread of scientific knowledge through the general public - particularly schools, qualified professionals and the academic community will be organised increasingly frequently (Open day, Summer Schools, Workshops, Conferences, etc.). 6. Implementation of the ISO 9001:2015 quality standard requirements in the research activities of the Centre. 10.3 Summary in English for evaluation In the next 5 years, CiiEM will concentrate its efforts in: 1. Consolidating the ongoing organization of the Research Centre, monitoring and promoting the adequate operation of its functional structures. An editorial committee will be created to manage internal and external communication. 2. Developing its research activity in the following topics and projects, under the coordination of the research areas: Forensic Science and Psychology LABPSI - RESEARCH IN PSYCHOLOGY Factors associated with bruxism and the effectiveness of cognitive behavioral stress management therapy Posttraumatic growth and depreciation Sleep and psychosocial factors Research Projects in Homicide, Femicide, Stalking in the context of intimate partner violence Adaptation and validation of an antisocial behaviour risk assessment methodology for children up to 11 Biopsychosocial characterization of recidivism of violent inmates Elder Domestic Violence Risk Assessment and Management(AGED - Assessment Guidelines for Elder Domestic Violence) LABFORSCILAB - RESEARCH IN FORENSIC APPLIED SCIENCES Amyloidogenicity propensity prediction Synthetic cannabinoids structure and receptor interaction Forensic soilanalysis for intelligence purposes Ballpoint pen identification through ink chemical analysis LCFPEM - FORENSIC PSYCHOLOGY, GENETIC AND TOXICOLOGY INTEGRATIVE RESEARCH Post Translational Modifications and Neurodegeneration Identification and assessment of new psychoactive substances in a European Network Impact of the Psychoactive Generated Compounds of NPS in vascularization, angiogenesis and neurodegeneration Understanding the real Toxicological Impact of Third Generation Synthetic Cannabinoids Determining ink and volatile solvent changes over time to create a molecular clock for documents Environmental Health WDXRFLab Molecular Design for Dental Restauration Long-term effects of altered bone turnover on glucose metabolism MORPHOLOGY LABORATORY Construction of a 3D virtual anatomy University within the UNESCO Chair in Digital Anatomy, presided by Prof. Vincent Delmas, based at the Anatomy Laboratory of University Paris Descartes, to which Egas Moniz belongs since September 2017 Public Health Microbiology Investigation of new vaccines and drugs to treat HIV infection Determinants of neutralizing antibody response in HIV-1 individuals in Angola Characterization of a potential case of generational HIV transmission Characterization of the 2016 yellow fever epidemic in Angola Antiviral resistance in HIV, HBV and HCV Searching APOBEC protein responsible for inhibition of HIV-2 vif deficient vírus Breast cancer therapeutics with Vif Citotoxicity assays of several dental materials, using cell lines in culture Effect of periodontal treatment on insulin resistance and inflammatory status improvement Relationship between periodontic pathogenic microorganisms and free-living amoebae Antibiotic resistance in the environment and in health care settings Fungal infections with emerging Candida pathogenic species Clinical Research CDRU - CLINICAL DENTAL RESEARCH UNIT Egas Moniz oral health database Epidemiology and implications for health care research and oral and medical education Periodontitis and Systemical Diseases Diabetes Cardiovascular disease and obesity Low-birth-weight and premature birth Osteoporosis Biomaterials in Periodontology and Implantology Bone substitutes and membranes Collagen matrices Dental implants Utilization of a particulate of autogenous dentin in bone regeneration Controlled drug release Hydrogels for biomedical applications New surgical techniques in periodontology and implantology 3D assessment of multiple techniques (intra-oral scanner and CBCT - cone beam computed tomography) Other Inflammatory biomarkers in saliva Students' Clinical Performance 3. Enhancing external cooperation and participation in scientific networks. It is essential that the scientific work at CiiEM remains current and connected to the most significant scientific international trends. To this purpose CiiEM will continue to encourage the formation of scientific partnerships and the participation of its members in international meetings and networks giving priority to participation in international projects. 4. Extending the involvement of CiiEM in postgraduate teaching activities (PhD). CiiEM hosts Bachelors, Masters and PhD students from Egas Moniz and other universities. Their theses will be monitored, expanded and the development of conditions for full high quality support will be a priority. 5. Organizing an international Congress and other dissemination iniciatives Results from the ongoing work are presented annually in the CiiEM Congress, held jointly with international partner institutions, and the abstracts published in a highly ranked International Open Access journal. After the publication of the abstract book of the 2nd CiiEM Congress, negotiations with Annals of Medicine for a multi-year agreement to continue hosting these publications are progressing well. Annals of Medicine spans a wide range of biomedical subjects and has a high visibility among the scientific community as shown by its IF of 3.87, ranking it in the top 10%. The following seminar series will be continued for the foreseeable future: by the Research Areas (4/year), by the Research Laboratories (2/year) and via Clinical Meetings (monthly). Ad hoc seminars and courses will be held frequently. Other initiatives aiming to spread the knowledge produced at CiiEM through various societal actors will be carried out (Publications, Open day, Summer Schools, Conferences, Workshops etc.). 6. Implementation of the ISO 9001:2015 quality standard requirements. The functioning of CiiEM processes will be tuned to comply with ISO 9001:2015. This will involve an increased monitoring and perfectioning of procedures carried out by the laboratories and the CiiEM as a whole.

Institutions

Main Institutions

  • Instituto Universitário Egas Moniz Centro de Investigação Interdisciplinar Egas Moniz (IUEM CiiEM)
  • Egas Moniz - Cooperativa de Ensino Superior Crl (EgasMonizCES)

Funding 587.450,00 €

Fundação para a Ciência e a Tecnologia (FCT) - Portugal

587.450,00 €