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Activity Funded

Coimbra Institute for Biomedical Imaging and Translational Research

Centro de Imagem Biomédica e Investigação Translacional

Reference
UID/PRR/04950/2025
Project Start Date
2025-01-01
Project End Date
2026-06-30
Principal Investigator
Scientific Area
Medical and health sciences
Funding Program
Avaliação UID 2023/2024 PRR

Abstract

CIBIT is based at ICNAS, University of Coimbra, which hosts an infrastructure of the National Roadmap, implemented after international evaluation. Our Research Unit –previously integrated in CNC.IBILI with an international panel evaluation of Excellent– features a fully translational biomedical research effort, from the design of new molecular probes to human imaging of structure, chemistry and function with a focus on the human brain and biomarker research. ICNAS integrates multimodal facilities from Molecular Imaging using locally produced (in-house Cyclotron) probes to MR Imaging. We represent the Medical Imaging Branch of EU funded EuroBioimaging Network. Our mission includes basic, translational research and development and exploitation of new imaging Technologies driving the development of and/or access to state-of-the-art imaging and physiological instrumentation (MRI, EEG, TMS, PET, CT, fNIR (and combined modalities). Our leadership of initiatives such as the Brain Imaging Network are instrumental for the national scientific development and we focus on Clinical Neuroscience and Biomarker development approaches. Our participation in the National Roadmap, approved after international evaluation, is justified by the large set of modalities involved (Cyclotron with 11C Radiochemistry for Molecular Imaging, PET/CT, SPECT, 3T MR, TMS, fNIR), all centralized at our central facility at the University of Coimbra, Portugal. The range of our activities covers all the Medical Imaging workpackages of Eurobioimaging, from translational research using Molecular and Functional Imaging techniques to basic and clinical research in neuroscience, including clinical trials in areas where functional and molecular imaging biomarkers are critical (in neuroscience, cardiology, and oncology). The level of complementarity is very high also because of our specialized radiochemistry Unit that can synthesize new compounds for molecular imaging in humans (and animals) using several tracers, including 11C. Moreover, we have also the possibility of programming new MR imaging approaches taking advantage of the research collaboration with Siemens and interactions with centers such as John Hopkins Hospital, Maastricht BIC and others. We share patient databases of a few hundred subjects (including Neurodevelopmental disorders and Alzheimer’s Disease, with several imaging modalities). We have several running clinical trial contracts, investigator-driven trials and research agreements with the industry.

Institutions

Main Institutions

  • Centro de Imagem Biomédica e Investigação Translacional (CIBIT/UC)
  • Universidade de Coimbra (UC)

Funding 948.195,47 €

Fundação para a Ciência e a Tecnologia (FCT) - Portugal

0,00 €

União Europeia - Estrutura de Missão Recuperar Portugal (UE - EMRP)

948.195,47 €
  • 2025-01-01 a 2026-12-31
  • UID/PRR/04950/2025